Not since Serena Williams defeated her sister Venus in two sets three years ago has an American played for the Australian Open title.

Kenin had never even reached the quarterfinals of a Grand Slam tournament until this week but now has her sights set on what would be a major upset.

The 21-year-old has dropped just one set in the tournament—against Coco Gauff in the fourth round—and overcame Tunisia’s Ons Jabeur 6-4, 6-4 in the quarterfinals.

Kenin needed five set points to clinch the opening set, before saving three break points while down 2-3 in the second set.

The American admitted preventing Jabeur from taking a 4-2 lead had been the pivotal moment in the match.

“After that [saving the break point] I got my momentum and started playing better,” the 21-year-old said. I’m super excited. It was a tough match."

Barty, meanwhile, reached her first Australian Open semifinal after defeating No. 7 seed Petra Kvitova 7-6 (8-6), 6-2.

The World No. 1 won the French Open last year and is aiming to become the first Australian woman to play in the final at Melbourne Park since Wendy Turnbull in 1980 and the first to win the women’s singles tournament since Chris O’Neil in 1978.

In 1984, Turnbull was also the last Australian woman to reach the semifinal on home soil until Barty emulated her on Wednesday.

“It’s been absolutely incredible,” she said. “I knew I had to bring my best against Petra. That first set was crucial and it was good to get a quick start in the second.”

In the other semifinal, reigning Wimbledon champion Simona Halep takes on two-time Grand Slam winner Garbine Muguruza.

Halep, the No. 4 seed, thrashed Estonia’s Anett Kontaveit 6-1, 6-1, while Muguruza defeated Russia’s Anastasia Pavlyuchenkova 7-5, 6-3.

Here’s everything you need to know to keep up with the semifinals.

Semifinals start time

The semifinals of the Australian Open get underway at 2 p.m. local time on Thursday.

However, because of the 16-hour difference between Melbourne and the east coast of the U.S., matches get underway at 10 p.m. ET on Wednesday evening.

TV channel

Coverage on ESPN2 begins at 10 p.m. ET on Wednesday and runs until 2 a.m. on Thursday, before resuming on ESPN at 3:30 a.m. on Thursday and running until 6 a.m. ET.

A replay will be available on ESPN2 between 2 p.m. and 5 p.m. on Thursday.

Live stream

Fans can watch the action online via the WatchESPN app and on ESPN.com.

Semifinals schedule (All times ET)

Wednesday, January 29

Ashleigh Barty (1) vs. Sofia Kenin (14)—Not before 10 p. m. Simona Halep (4) vs. Garbine Muguruza—Not before 11:30 p. m.

Thursday, January 30

Roger Federer (2) vs. Novak Djokovic (2)—3:30 a. m.

Australian Open odds

According to Oddschecker, Novak Djokovic is a 9/20 favorite to defend his title, followed by Rafael Nadal at 22/5. Alexander Zverev and Roger Federer are both 14/1 outsiders.

World No. 1 Ashleigh Barty is a 34/25 favorite to win the women’s tournament, with Simona Halep at 2/1 and Garbine Muguruza at 4/1 respectively. Sofia Kenin is a 15/2 outsider.